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Literature summary for 1.1.1.B40 extracted from

  • Claus, R.; Wagner, A.; Lambert, T.
    Characterization of 11beta-hydroxysteroid dehydrogenase activity in testicular tissue of control and GnRH-immunized boars as a possible regulator of spermatogenesis (2005), Exp. Clin. Endocrinol. Diabetes, 113, 262-267.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
cortisol + NAD+ Sus scrofa isozyme 11beta-HSD2 catalyzes the reverse reaction of 11beta-HSD1 with cofactor NAD+ cortisone + NADH
-
ir
additional information Sus scrofa the enzyme plays a role in control of cortisol and spermatogenesis ?
-
?

Organism

Organism UniProt Comment Textmining
Sus scrofa Q8MKG1
-
-

Source Tissue

Source Tissue Comment Organism Textmining
testis isozyme expression analysis Sus scrofa
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
isozyme activity in testicular tissue and glucocorticoid concentration, overview; isozyme activity in testicular tissue and glucocorticoid concentration, overview Sus scrofa

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
cortisol + NAD+ isozyme 11beta-HSD2 catalyzes the reverse reaction of 11beta-HSD1 with cofactor NAD+ Sus scrofa cortisone + NADH
-
ir
additional information the enzyme plays a role in control of cortisol and spermatogenesis Sus scrofa ?
-
?

Synonyms

Synonyms Comment Organism
11beta-HSD 2
-
Sus scrofa

Cofactor

Cofactor Comment Organism Structure
NAD+
-
Sus scrofa

Expression

Organism Comment Expression
Sus scrofa isozyme expression analysis additional information