Inhibitors | Comment | Organism | Structure |
---|---|---|---|
5-(3-bromo-4-hydroxybenzyl)-3-(4-methoxyphenyl)-1,3-thiazol-2-one | starting compound for high-throughput screening. IC50 value 570 nM in cell-based assay | Homo sapiens | |
5-(3-bromo-4-hydroxybenzylidene)-3-(4-methoxyphenyl)-2-thioxo-1,3-thiazolidin-4-one | compound demonstrates significant selectivity for isoform 17beta-hydroxysteroid dehydrogenase type 3 over the related isoenzymes and nuclear receptors. IC50 value 14 nM in cell-based assay | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P37058 | - |
- |
Synonyms | Comment | Organism |
---|---|---|
3beta-hydroxysteroid dehydrogenase type 3 | - |
Homo sapiens |