Literature summary for 1.1.1.62 extracted from

Day, J.M.; Tutill, H.J.; Newman, S.P.; Purohit, A.; Lawrence, H.R.; Vicker, N.; Potter, B.V.; Reed, M.J.
17beta-Hydroxysteroid dehydrogenase type 1 and type 2: association between mRNA expression and activity in cell lines (2006), Mol. Cell. Endocrinol., 248, 246-249.

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
estrone + NAD(P)H + H+	Homo sapiens	-	estradiol + NAD(P)+	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
HEK-293-EBNA cell	transfected with type 1 cDNA, high activity	Homo sapiens	-
JEG-3 cell	high activity	Homo sapiens	-
MCF-7 cell	MCF-7.8H cell derived from MCF-7 via transfection, high enzyme activity	Homo sapiens	-
MDA-MB-231 cell	weak activity	Homo sapiens	-
T-47D cell	high activity	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
estrone + NAD(P)H + H+	-	Homo sapiens	estradiol + NAD(P)+	-	?

Synonyms

Synonyms	Comment	Organism
17beta-HSD1	-	Homo sapiens
17beta-hydroxysteroid dehydrogenase type 1	-	Homo sapiens

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Release 2023.1 (January 2023)