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Literature summary for 1.1.1.62 extracted from

  • Kaufmann, M.; Carstensen, J.; Husen, B.; Adamski, J.
    The tissue distribution of porcine 17beta-estradiol dehydrogenase and its induction by progesterone (1995), J. Steroid Biochem. Mol. Biol., 55, 535-539.
    View publication on PubMed
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
estrone + NADH Sus scrofa progesterone treatment of ovariectomized gilts stimulates oxidative activity in uterus, anterior pituitary, skeletal muscle and kidney, constitutive levels of activity in adrenals, lung and liver estradiol-17beta + NAD+
-
 ?

Organism

Organism UniProt Comment Textmining
Sus scrofa
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
adenohypophysis
-
 Sus scrofa
-
kidney proximal tubuli Sus scrofa
-
liver
-
 Sus scrofa
-
lung bronchial epithelium Sus scrofa
-
skeletal muscle diaphragm Sus scrofa
-
uterus luminal and glandular epithelium Sus scrofa
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
estradiol-17beta + NAD+
-
 Sus scrofa estrone + NADH
-
 ?
estrone + NADH progesterone treatment of ovariectomized gilts stimulates oxidative activity in uterus, anterior pituitary, skeletal muscle and kidney, constitutive levels of activity in adrenals, lung and liver Sus scrofa estradiol-17beta + NAD+
-
 ?
estrone + NADPH + H+
-
 Sus scrofa estradiol-17beta + NADP+
-
 ?

Cofactor

Cofactor Comment Organism Structure
NAD+ cofactor Sus scrofa
NADPH cofactor Sus scrofa