Literature summary for 1.1.1.60 extracted from

Ijau, R.K.; Herndon, C.A.; Hawes, J.W.
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus infuenzae (2000), J. Biol. Chem., 275, 38780-38786.

Search for more literature for 1.1.1.60

Cloned(Commentary)

Cloned (Comment)	Organism
overexpression in Escherichia coli	Haemophilus influenzae
overexpression in Escherichia coli	Escherichia coli

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
0.048	-	(R)-beta-hydroxybutyrate	-	Haemophilus influenzae
0.06	-	D-threonine	-	Haemophilus influenzae
0.28	-	D-glycerate	-	Escherichia coli
3.7	-	D-glycerate	-	Haemophilus influenzae
4.2	-	L-Glycerate	-	Escherichia coli

Organism

Organism	UniProt	Comment	Textmining
Escherichia coli	-	-	-
Haemophilus influenzae	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
of recombinant protein	Haemophilus influenzae
of recombinant protein	Escherichia coli

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
(R)-beta-hydroxybutyrate + NAD+	-	Haemophilus influenzae	?	-	?
(R)-glycerate + NAD(P)+	-	Haemophilus influenzae	tartronate semialdehyde + NAD(P)H	-	r
(R)-glycerate + NAD(P)+	-	Escherichia coli	tartronate semialdehyde + NAD(P)H	-	r
D-threonine + NAD+	-	Haemophilus influenzae	?	-	?
L-glycerate + NAD+	-	Escherichia coli	?	-	r
tartronate semialdehyde + NAD(P)H	-	Haemophilus influenzae	(R)-glycerate + NAD(P)+	-	r
tartronate semialdehyde + NAD(P)H	-	Escherichia coli	(R)-glycerate + NAD(P)+	-	r

Synonyms

Synonyms	Comment	Organism
beta-hydroxyacid dehydrogenase	-	Haemophilus influenzae
beta-hydroxyacid dehydrogenase	-	Escherichia coli

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Release 2023.1 (January 2023)