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Literature summary for 1.1.1.55 extracted from

  • Gupta, N.K.; Robinson, W.G
    Enzymic conversion of lactaldehyde to propanediol (1960), J. Biol. Chem., 235, 1609-1612.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
cysteine
-
Sus scrofa
Dimercaptopropanol
-
Sus scrofa
glutathione
-
Sus scrofa
p-chloromercuribenzoate
-
Sus scrofa
thioethanol
-
Sus scrofa

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.9
-
L-lactaldehyde
-
Sus scrofa

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-lactaldehyde + NADPH + H+ Spinacia oleracea
-
propane-1,2-diol + NADP+
-
r
L-lactaldehyde + NADPH + H+ Pseudomonas aeruginosa
-
propane-1,2-diol + NADP+
-
r
L-lactaldehyde + NADPH + H+ Sus scrofa the equilibrium greatly favors the reduction of L-lactaldehyde and can be reversed in the presence of high concentrations of propane-1,2-diol at high pH-values propane-1,2-diol + NADP+
-
r

Organism

Organism UniProt Comment Textmining
Pseudomonas aeruginosa
-
-
-
Spinacia oleracea
-
-
-
Sus scrofa
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Sus scrofa

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
Sus scrofa
-
heart
-
Sus scrofa
-
kidney
-
Sus scrofa
-
leaf
-
Spinacia oleracea
-
liver
-
Sus scrofa
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-lactaldehyde + NADPH + H+
-
Spinacia oleracea propane-1,2-diol + NADP+
-
r
L-lactaldehyde + NADPH + H+
-
Pseudomonas aeruginosa propane-1,2-diol + NADP+
-
r
L-lactaldehyde + NADPH + H+ the equilibrium greatly favors the reduction of L-lactaldehyde and can be reversed in the presence of high concentrations of propane-1,2-diol at high pH-values Sus scrofa propane-1,2-diol + NADP+
-
r

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.4
-
-
Sus scrofa