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Literature summary for 1.1.1.53 extracted from

  • Szymanski, E.S.; Furfine, C.S.
    20beta-Hydroxysteroid oxidoreductase. Kinetics and binding of corticosteroids and corticosteroid-21-aldehydes (1977), J. Biol. Chem., 252, 205-211.
    View publication on PubMed
Search for more literature for 1.1.1.53

Inhibitors

Inhibitors Comment Organism Structure
20beta-Hydroxycortisol
-
 Streptomyces exfoliatus
20beta-hydroxyprogesterone
-
 Streptomyces exfoliatus
additional information substrate and product inhibition Streptomyces exfoliatus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
additional information
-
 additional information
-
 Streptomyces exfoliatus
0.029
-
 NADH
-
 Streptomyces exfoliatus

Organism

Organism UniProt Comment Textmining
Streptomyces exfoliatus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
commercial preparation
-
 Streptomyces exfoliatus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
cortisone + NAD(P)H i.e. 17beta,21-dihydroxy-pregn-4-ene-3,11,20-trione Streptomyces exfoliatus 17alpha,20beta,21-trihydroxy-pregn-4-ene-3,11-dione + NAD(P)+
-
 ?