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Literature summary for 1.1.1.53 extracted from

  • Sweet, F.; Patrick, T.B.; Judd, M.
    Substrate characteristics of progesterone-albumin conjugates with 20beta-hydroxysteroid dehydrogenase (1978), Biochem. Biophys. Res. Commun., 83, 187-194.
    View publication on PubMed

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.00395
-
progesterone
-
Streptomyces exfoliatus
0.0251
-
21-hydroxyprogesterone
-
Streptomyces exfoliatus
1.43
-
21-Hemisuccinyloxyprogesterone
-
Streptomyces exfoliatus
2.19
-
11alpha-Hemisuccinyloxyprogesterone
-
Streptomyces exfoliatus
2.23
-
21-Acetoxyprogesterone
-
Streptomyces exfoliatus

Organism

Organism UniProt Comment Textmining
Streptomyces exfoliatus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
commercial preparation
-
Streptomyces exfoliatus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
11alpha-hemisuccinyloxyprogesterone + NADH
-
Streptomyces exfoliatus ?
-
?
21-acetoxyprogesterone + NADH
-
Streptomyces exfoliatus ?
-
?
21-hemisuccinyloxyprogesterone + NADH
-
Streptomyces exfoliatus ?
-
?
deoxycorticosterone + NADPH
-
Streptomyces exfoliatus 20,21-dihydroxypregn-4-ene-3-one + NADP+
-
?
progesterone + NAD(P)H
-
Streptomyces exfoliatus 20beta-hydroxy-pregn-4-ene-3-one + NAD(P)+
-
?