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Literature summary for 1.1.1.51 extracted from
- The induction, purification and characterization of 17beta-hydroxy-C19-steroid dehydrogenase of the female guinea pig kidney (1979), J. Steroid Biochem., 10, 187-193.
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.2 | - |
testosterone | cofactor NAD+ or NADP+ | Cavia porcellus |  |
| 0.2 | - |
5alpha-dihydrotestosterone | cofactor NAD+ or NADP+ | Cavia porcellus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytosol | - |
Cavia porcellus | 5829 | - |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 32000 | - |
gel filtration | Cavia porcellus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Cavia porcellus | - |
female | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| kidney | - |
Cavia porcellus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
- |
Cavia porcellus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 5alpha-dihydrotestosterone + NADP+ | - |
Cavia porcellus | 5alpha-androstane-3,17-dione + NADPH + H+ | - |
r | |
| testosterone + NAD(P)+ | - |
Cavia porcellus | androst-4-en-3,17-dione + NAD(P)H + H+ | - |
? | |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NADP+ | - |
Cavia porcellus | |
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