Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli | Trypanosoma brucei |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(2E)-2-cyano-3-(5-nitrofuran-2-yl)prop-2-enoic acid | - |
Trypanosoma brucei | |
2-methyl-5-nitrofuran-3-carboxylic acid | - |
Trypanosoma brucei | |
3,3',4,4'-tetramethyl-1H,1'H-2,2'-bipyrrole-5,5'-dicarboxylic acid | - |
Trypanosoma brucei | |
3-methyl-4-oxo-4,7-dihydro-5H-thiopyrano[3,4-b]furan-2-carboxylic acid | - |
Trypanosoma brucei | |
4,5-dichloro-1H-pyrrole-2-carboxylic acid | - |
Trypanosoma brucei | |
4-chloro-1H-pyrrole-2-carboxylic acid | - |
Trypanosoma brucei | |
4H-thieno[3,2-b]pyrrole-5-carboxylic acid | - |
Trypanosoma brucei | |
5-(ethoxycarbonyl)-3,4-dimethyl-1H-pyrrole-2-carboxylic acid | - |
Trypanosoma brucei | |
potassium 3,4-dioxo-3,4-dihydronaphthalene-1-sulfonate | - |
Trypanosoma brucei | |
sodium (4E)-4-(hydroxyimino)-3-oxo-1,2,3,4-tetrahydronaphthalene-1-sulfonate | - |
Trypanosoma brucei | |
[(5-nitrofuran-2-yl)methylidene]propanedioic acid | - |
Trypanosoma brucei |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Trypanosoma brucei | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
6-phospho-D-gluconate + NADP+ | - |
Trypanosoma brucei | D-ribulose 5-phosphate + CO2 + NADPH + H+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
6PGDH | - |
Trypanosoma brucei |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7 | - |
assay at | Trypanosoma brucei |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | - |
Trypanosoma brucei |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.0058 | - |
pH 7.0, temperature not specified in the publication | Trypanosoma brucei | (2E)-2-cyano-3-(5-nitrofuran-2-yl)prop-2-enoic acid | |
0.028 | - |
pH 7.0, temperature not specified in the publication | Trypanosoma brucei | 2-methyl-5-nitrofuran-3-carboxylic acid | |
0.042 | - |
pH 7.0, temperature not specified in the publication | Trypanosoma brucei | 4H-thieno[3,2-b]pyrrole-5-carboxylic acid | |
0.042 | - |
pH 7.0, temperature not specified in the publication | Trypanosoma brucei | 4,5-dichloro-1H-pyrrole-2-carboxylic acid | |
0.043 | - |
pH 7.0, temperature not specified in the publication | Trypanosoma brucei | 4-chloro-1H-pyrrole-2-carboxylic acid | |
0.045 | - |
pH 7.0, temperature not specified in the publication | Trypanosoma brucei | 5-(ethoxycarbonyl)-3,4-dimethyl-1H-pyrrole-2-carboxylic acid | |
0.051 | - |
pH 7.0, temperature not specified in the publication | Trypanosoma brucei | 3-methyl-4-oxo-4,7-dihydro-5H-thiopyrano[3,4-b]furan-2-carboxylic acid | |
0.053 | - |
pH 7.0, temperature not specified in the publication | Trypanosoma brucei | potassium 3,4-dioxo-3,4-dihydronaphthalene-1-sulfonate | |
0.056 | - |
pH 7.0, temperature not specified in the publication | Trypanosoma brucei | [(5-nitrofuran-2-yl)methylidene]propanedioic acid | |
0.073 | - |
pH 7.0, temperature not specified in the publication | Trypanosoma brucei | sodium (4E)-4-(hydroxyimino)-3-oxo-1,2,3,4-tetrahydronaphthalene-1-sulfonate | |
0.114 | - |
pH 7.0, temperature not specified in the publication | Trypanosoma brucei | 3,3',4,4'-tetramethyl-1H,1'H-2,2'-bipyrrole-5,5'-dicarboxylic acid |