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Literature summary for 1.1.1.44 extracted from
- Kinetic analysis of 6-phosphogluconate dehydrogenase from bass liver: Effects of temperature and pH on its catalytic function (1988), Arch. Biochem. Biophys., 262, 130-141.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| NADPH | - |
Dicentrarchus labrax |  |
| phosphoenolpyruvate | - |
Dicentrarchus labrax | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.00088 | - |
NADP+ | - |
Dicentrarchus labrax | |
| 0.02666 | - |
6-phosphogluconate | - |
Dicentrarchus labrax | |
| 3.33 | - |
Mg2+ | - |
Dicentrarchus labrax | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | activated by MgCl2 | Dicentrarchus labrax | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 6-phospho-D-gluconate + NADP+ | Carassius carassius | - |
D-ribulose 5-phosphate + CO2 + NADPH + H+ | - |
r | |
| 6-phospho-D-gluconate + NADP+ | Dicentrarchus labrax | enzyme specific for the oxidative pentose phosphate pathway | D-ribulose 5-phosphate + CO2 + NADPH + H+ | - |
r | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Carassius carassius | - |
crucian carp | - |
| Dicentrarchus labrax | - |
bass | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Dicentrarchus labrax |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Dicentrarchus labrax | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 6-phospho-D-gluconate + NADP+ | - |
Dicentrarchus labrax | D-ribulose 5-phosphate + CO2 + NADPH + H+ | - |
r | |
| 6-phospho-D-gluconate + NADP+ | - |
Carassius carassius | D-ribulose 5-phosphate + CO2 + NADPH + H+ | - |
r | |
| 6-phospho-D-gluconate + NADP+ | enzyme specific for the oxidative pentose phosphate pathway | Dicentrarchus labrax | D-ribulose 5-phosphate + CO2 + NADPH + H+ | - |
r | |
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