Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Selenite | inactivates IDPm | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | IDPm | Homo sapiens | 5739 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
HeLa cell | - |
Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
IDPm | - |
Homo sapiens |
mitochondrial NADP+-dependent isocitrate dehydrogenase | - |
Homo sapiens |
NADP+-dependent isocitrate dehydrogenase | - |
Homo sapiens |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | transfection of HeLa cells with siRNA leading to decreased activity of IDPm and enhanced susceptibility of the cells to selenite-induced apoptosis, overview | additional information |
General Information | Comment | Organism |
---|---|---|
physiological function | the mitochondrial NADP+-dependent isocitrate dehydrogenase controls the mitochondrial redox balance by supplying NADPH for antioxidant systems | Homo sapiens |