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Literature summary for 1.1.1.42 extracted from

  • Karlstroem, M.; Steen, I.H.; Madern, D.; Fedoey, A.E.; Birkeland, N.K.; Ladenstein, R.
    The crystal structure of a hyperthermostable subfamily II isocitrate dehydrogenase from Thermotoga maritima (2006), FEBS J., 273, 2851-2868.
    View publication on PubMed

Crystallization (Commentary)

Crystallization (Comment) Organism
dimeric apoform Thermotoga maritima

Protein Variants

Protein Variants Comment Organism
D389N reduction in apparent melting temperature by 21.8°C compared to wild-type Thermotoga maritima
F205M reduction in apparent melting temperature by 3.5°C compared to wild-type Thermotoga maritima
R186M no change in apparent melting temperature compared to wild-type Thermotoga maritima

Organism

Organism UniProt Comment Textmining
Thermotoga maritima Q9X0N2
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-

Subunits

Subunits Comment Organism
dimer and tetramer, crystallization data and analytical ultracentrifugation Thermotoga maritima
tetramer and dimer, crystallization data and analytical ultracentrifugation Thermotoga maritima