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Literature summary for 1.1.1.42 extracted from

  • Palomo, J.; Gallardo, F.; Suarez, M.F.; Canovas, F.M.
    Purification and characterization of NADP+-linked isocitrate dehydrogenase from scots pine (1998), Plant Physiol., 118, 617-626.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.1.1.42

Inhibitors

Inhibitors Comment Organism Structure
2-oxoglutarate inhibition by chelating Mg2+ Pinus spp.
5'-ADP inhibition by chelating Mg2+ Pinus spp.
ATP inhibition by chelating Mg2+ Pinus spp.

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.01
-
 NADP+
-
 Pinus spp.
0.08
-
 D,L-isocitrate
-
 Pinus spp.

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Pinus spp. 5829
-

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ absolute requirement for divalent cations Pinus spp.

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
46000
-
 alpha2, 2 * 46000, SDS-PAGE Pinus spp.
95000
-
 gel filtration Pinus spp.

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
isocitrate + NADP+ Pinus spp.
-
 2-oxoglutarate + NADPH + H+ + CO2
-
 ?

Organism

Organism UniProt Comment Textmining
Pinus spp.
-
 Scots pine
-

Purification (Commentary)

Purification (Comment) Organism
-
 Pinus spp.

Source Tissue

Source Tissue Comment Organism Textmining
cotyledon
-
 Pinus spp.
-
whole plant
-
 Pinus spp.
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
isocitrate + NADP+
-
 Pinus spp. 2-oxoglutarate + NADPH + H+ + CO2
-
 ?

Subunits

Subunits Comment Organism
dimer alpha2, 2 * 46000, SDS-PAGE Pinus spp.

Cofactor

Cofactor Comment Organism Structure
NADP+
-
 Pinus spp.