Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.1.1.41 extracted from

  • Evans, C.T.; Ratledge, C.
    The role of the mitochondrial NAD+:isocitrate dehydrogenase in lipid accumulation by the oleaginous yeast Rhodosporidium toruloides CBS 14 (1985), Can. J. Microbiol., 31, 845-850.
No PubMed abstract available

Inhibitors

Inhibitors Comment Organism Structure
2-oxoglutarate
-
Rhodotorula toruloides
ATP
-
Rhodotorula toruloides
citrate
-
Rhodotorula toruloides
L-glutamate
-
Rhodotorula toruloides
NADH
-
Rhodotorula toruloides
oxaloacetate
-
Rhodotorula toruloides

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
Rhodotorula toruloides 5739
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
191800
-
gel filtration Rhodotorula toruloides

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
isocitrate + NAD+ Rhodotorula toruloides
-
2-oxoglutarate + CO2 + NADH + H+
-
?

Organism

Organism UniProt Comment Textmining
Rhodotorula toruloides
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Rhodotorula toruloides

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
7.3
-
-
Rhodotorula toruloides

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
isocitrate + NAD+
-
Rhodotorula toruloides 2-oxoglutarate + CO2 + NADH + H+
-
?

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
-
-
full loss in activity in a few hours Rhodotorula toruloides

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.2 8.2
-
Rhodotorula toruloides

Cofactor

Cofactor Comment Organism Structure
NAD+
-
Rhodotorula toruloides