Any feedback?
Literature summary for 1.1.1.40 extracted from
- Light activation of NADP malic enzyme in leaves of maize: marginal increase in activity, but marked change in regulatory properties of enzyme (2003), J. Plant Physiol., 160, 51-56.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| citrate | activation is increased by light exposure | Zea mays |  |
| additional information | activation by light with 30% increased Vmax, activation by light is reduced by addition of dithiols | Zea mays | |
| succinate | activation is increased by light exposure | Zea mays | |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| additional information | feedback inhibition is reduced by illumination | Zea mays | |
| oxalate | inhibition is decreased by light exposure | Zea mays | |
| pyruvate | inhibition is decreased by light exposure | Zea mays | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.26 | - |
L-malate | pH 8.0, 30°C, light | Zea mays | |
| 0.28 | - |
L-malate | pH 8.0, 30°C, dark | Zea mays | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | - |
Zea mays | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| (S)-malate + NADP+ | Zea mays | - |
pyruvate + CO2 + NADPH | - |
? | |
| additional information | Zea mays | enzyme is regulated by light and dithiols, such as dithioerythritol | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Zea mays | - |
cv. VMH 404 | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| leaf | - |
Zea mays | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| (S)-malate + NADP+ | - |
Zea mays | pyruvate + CO2 + NADPH | - |
? | |
| additional information | enzyme is regulated by light and dithiols, such as dithioerythritol | Zea mays | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| NADP malic enzyme | - |
Zea mays |
| NADP-ME | - |
Zea mays |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 30 | - |
assay at | Zea mays |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 8 | - |
assay at | Zea mays |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NADP+ | - |
Zea mays | |
Ki Value [mM]
| Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.18 | - |
oxalate | pH 8.0, 30°C, dark | Zea mays | |
| 0.3 | - |
oxalate | pH 8.0, 30°C, light | Zea mays | |
| 1.3 | - |
pyruvate | pH 8.0, 30°C, dark | Zea mays | |
| 2.6 | - |
pyruvate | pH 8.0, 30°C, light | Zea mays | |
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Release 2023.1 (January 2023)
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