Inhibitors | Comment | Organism | Structure |
---|---|---|---|
oxalate | - |
Oryctolagus cuniculus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.014 | - |
NADP+ | activation by Mn2+ | Oryctolagus cuniculus | |
0.025 | - |
NADP+ | activation by Mg2+ | Oryctolagus cuniculus | |
1.06 | - |
(S)-malate | activation by Mn2+ | Oryctolagus cuniculus | |
1.06 | - |
(S)-malate | in the presence of 10 mM Mn2+, at pH 7.4 and 25°C | Oryctolagus cuniculus | |
3.63 | - |
(S)-malate | activation by Mg2+ | Oryctolagus cuniculus | |
3.63 | - |
(S)-malate | in the presence of 10 mM Mg2+, at pH 7.4 and 25°C | Oryctolagus cuniculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Oryctolagus cuniculus | 5739 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | requires low concentration of Mn2+ or Mg2+ for activity, Km: 0.24 mM | Oryctolagus cuniculus | |
Mn2+ | Km: 0.01 mM | Oryctolagus cuniculus | |
Mn2+ | requires low concentration of Mn2+ or Mg2+ for activity | Oryctolagus cuniculus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
180000 | - |
gel filtration | Oryctolagus cuniculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Oryctolagus cuniculus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Oryctolagus cuniculus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
cardiac muscle | - |
Oryctolagus cuniculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(S)-malate + NADP+ | - |
Oryctolagus cuniculus | pyruvate + CO2 + NADPH | - |
r | |
Oxaloacetate | - |
Oryctolagus cuniculus | Pyruvate + CO2 | - |
? | |
pyruvate + CO2 + NADPH | 6% of the activity of the NADP+-linked oxidative decarboxylation of malate | Oryctolagus cuniculus | L-malate + NADP+ | - |
r |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7 | 8 | - |
Oryctolagus cuniculus |