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Literature summary for 1.1.1.39 extracted from

  • Niedzwiecka, N.; Gronczewska, J.; Skorkowski, E.F.
    NAD-preferring malic enzyme: localization, regulation and its potential role in herring (Clupea harengus) sperm cells (2017), Fish Physiol. Biochem., 43, 351-360.
    View publication on PubMed
Search for more literature for 1.1.1.39

Inhibitors

Inhibitors Comment Organism Structure
ATP the enzyme is competitively inhibited by ATP up to 10fold. Addition of 1 mM or 5 mM fumarate reverses ATP-dependent inhibition of the enzyme to 55 or 70% of its maximum activity, respectively Clupea harengus

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Clupea harengus 5739
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
61000
-
 x * 61000, SDS-PAGE Clupea harengus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(S)-malate + NAD+ Clupea harengus
-
 pyruvate + CO2 + NADH
-
 r

Organism

Organism UniProt Comment Textmining
Clupea harengus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
sperm
-
 Clupea harengus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(S)-malate + NAD+
-
 Clupea harengus pyruvate + CO2 + NADH
-
 r

Subunits

Subunits Comment Organism
? x * 61000, SDS-PAGE Clupea harengus

Synonyms

Synonyms Comment Organism
NAD-ME
-
 Clupea harengus
NAD-preferring malic enzyme
-
 Clupea harengus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7
-
-
 Clupea harengus

Cofactor

Cofactor Comment Organism Structure
NAD+
-
 Clupea harengus