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Literature summary for 1.1.1.37 extracted from

  • Pracharoenwattana, I.; Cornah, J.E.; Smith, S.M.
    Arabidopsis peroxisomal malate dehydrogenase functions in beta-oxidation but not in the glyoxylate cycle (2007), Plant J., 50, 381-390.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
genes pmdh1 and pmdh2 Arabidopsis thaliana

Protein Variants

Protein Variants Comment Organism
additional information construction of enzyme-deficient mutants by pmdh1 and pmdh2 genes disruption by T-DNA insertion, mutant seedlings mobilize their triacylglycerol very slowly and growth are insensitive to 2,4-dichlorophenoxybutyric acid, phenotype, overview Arabidopsis thaliana

Inhibitors

Inhibitors Comment Organism Structure
2,4-dichlorophenoxybutyric acid
-
Arabidopsis thaliana

Localization

Localization Comment Organism GeneOntology No. Textmining
peroxisome
-
Arabidopsis thaliana 5777
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(S)-malate + NAD+ Arabidopsis thaliana the peroxisomal malate dehydrogenase functions in beta-oxidation, serving to reoxidize NADH, but not in the glyoxylate cycle oxaloacetate + NADH + H+
-
r

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana
-
the Arabidopsis genome encodes eight putative NAD+-MDH enzymes
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(S)-malate + NAD+
-
Arabidopsis thaliana oxaloacetate + NADH + H+
-
r
(S)-malate + NAD+ the peroxisomal malate dehydrogenase functions in beta-oxidation, serving to reoxidize NADH, but not in the glyoxylate cycle Arabidopsis thaliana oxaloacetate + NADH + H+
-
r

Synonyms

Synonyms Comment Organism
NAD+-MDH enzymes
-
Arabidopsis thaliana
peroxisomal NAD+-malate dehydrogenase 1
-
Arabidopsis thaliana
peroxisomal NAD+-malate dehydrogenase 2
-
Arabidopsis thaliana
PMDH1
-
Arabidopsis thaliana
PMDH2
-
Arabidopsis thaliana

Cofactor

Cofactor Comment Organism Structure
NAD+ dependent on Arabidopsis thaliana
NADH dependent on Arabidopsis thaliana