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Literature summary for 1.1.1.37 extracted from

  • Harris, D.G.; Marx, D.P.; Anderson, J.M.; McCune, R.W.; Zimmerman, S.S.
    Kinetic and molecular modeling of nucleoside and nucleotide inhibition of malate dehydrogenase (2002), Nucleosides Nucleotides Nucleic Acids, 21, 813-823.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
ADP competitive Sus scrofa
AMP competitive Sus scrofa
ATP competitive Sus scrofa
cAMP competitive Sus scrofa

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
Sus scrofa 5739
-

Organism

Organism UniProt Comment Textmining
Sus scrofa
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
heart
-
Sus scrofa
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
oxaloacetate + NADH
-
Sus scrofa L-malate + NAD+
-
r

Cofactor

Cofactor Comment Organism Structure
NAD+
-
Sus scrofa
NADH
-
Sus scrofa

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.56
-
cAMP pH 7.4 Sus scrofa
0.95
-
AMP pH 7.4 Sus scrofa
1.34
-
ADP pH 7.4 Sus scrofa
1.36
-
ATP pH 7.4 Sus scrofa