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Literature summary for 1.1.1.37 extracted from

  • Ma, H.; Kubicek, C.P.; Roehr, M.
    Malate dehydrogenase isoenzymes in Aspergillus niger (1981), FEMS Microbiol. Lett., 12, 147-151.
No PubMed abstract available

Inhibitors

Inhibitors Comment Organism Structure
ATP
-
Aspergillus niger
oxaloacetate
-
Aspergillus niger

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.083
-
oxaloacetate mitochondrial MDH Aspergillus niger
0.09
-
oxaloacetate cyt MDH Aspergillus niger
0.14
-
NADH mit MDH Aspergillus niger
0.192
-
NADH cytosolic MDH Aspergillus niger

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
Aspergillus niger 5737
-
mitochondrion
-
Aspergillus niger 5739
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
35000
-
2 * 35000, SDS-PAGE Aspergillus niger
68000
-
gel filtration Aspergillus niger

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
malate + NAD+ Aspergillus niger
-
oxaloacetate + NADH + H+
-
r
malate + NAD+ Aspergillus niger B60
-
oxaloacetate + NADH + H+
-
r

Organism

Organism UniProt Comment Textmining
Aspergillus niger
-
-
-
Aspergillus niger B60
-
-
-

Purification (Commentary)

Purification (Comment) Organism
2 isoenzymes, cytoplasmic and mitochondrial Aspergillus niger

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(S)-malate + NAD+
-
Aspergillus niger oxaloacetate + NADH + H+
-
r
(S)-malate + NAD+
-
Aspergillus niger B60 oxaloacetate + NADH + H+
-
r
malate + NAD+
-
Aspergillus niger oxaloacetate + NADH + H+
-
r
malate + NAD+
-
Aspergillus niger B60 oxaloacetate + NADH + H+
-
r
oxaloacetate + NADH
-
Aspergillus niger L-malate + NAD+
-
r
oxaloacetate + NADH
-
Aspergillus niger B60 L-malate + NAD+
-
r

Subunits

Subunits Comment Organism
dimer 2 * 35000, SDS-PAGE Aspergillus niger