Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.1.1.34 extracted from

  • Gibson, D.M.; Parker, R.A.
    Hydroxymethylglutaryl-coenzyme A reductase (1987), The Enzymes, 2nd Ed. (Boyer, P. D. , Lardy, H. , Myrbäck, K. , eds. ), 18, 179-215.
No PubMed abstract available
Search for more literature for 1.1.1.34

Inhibitors

Inhibitors Comment Organism Structure
Compactin
-
 Rattus norvegicus
lovastatin
-
 Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
endoplasmic reticulum
-
 Rattus norvegicus 5783
-
microsome
-
 Rattus norvegicus
-
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
100000
-
 PAGE Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3-hydroxy-3-methylglutaryl-CoA + NADPH Rattus norvegicus
-
 (R)-mevalonate + CoA + NADP+
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3-hydroxy-3-methylglutaryl-CoA + NADPH
-
 Rattus norvegicus (R)-mevalonate + CoA + NADP+
-
 ?

Cofactor

Cofactor Comment Organism Structure
NADPH
-
 Rattus norvegicus