Crystallization (Comment) | Organism |
---|---|
sitting-drop vapor-diffusion method at 4°C from a 15-20 mg/ml enzyme solution equilibrated with 0.1 M potassium phosphate buffer pH 6.9-7.1, 0.1 mM ZnSO4, 1 mM dithiothreitol, 12-15% PEG8000. Binary complex with substrate 12-hydroxydodecanoic acid and a ternary complex with NAD+ and the inhibitor dodecanoic acid are determined at 2.0 and 2.3 A resolution by X-ray crystallography using the anomalous diffraction signal of zinc | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
dodecanoic acid | - |
Homo sapiens |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Zinc | mettaloenzyme | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
12-hydroxydodecanoic acid + glutathione + NAD+ | - |
Homo sapiens | S-(11-carboxy)undecanyl-glutathione + NADH + H+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ADH3 | - |
Homo sapiens |
c-ADH | - |
Homo sapiens |
class III alcohol dehydrogenase | - |
Homo sapiens |
EC 1.2.1.1 | formerly, part transferred | Homo sapiens |
FDH | incorrect | Homo sapiens |
formaldehyde dehydrogenase | incorrect | Homo sapiens |
formaldehyde dehydrogenase (glutathione) | incorrect | Homo sapiens |
formic dehydrogenase | incorrect | Homo sapiens |
GD-FAlDH | - |
Homo sapiens |
Glutathione-dependent formaldehyde dehydrogenase | incorrect | Homo sapiens |
GS-FDH | incorrect | Homo sapiens |
NAD- and glutathione-dependent formaldehyde dehydrogenase | - |
Homo sapiens |
NAD-dependent formaldehyde dehydrogenase | - |
Homo sapiens |
NAD-linked formaldehyde dehydrogenase | incorrect | Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Homo sapiens |