Any feedback?
Literature summary for 1.1.1.284 extracted from
- Maize glutathione-dependent formaldehyde dehydrogenase. Protein sequence and catalytic properties (1999), Planta, 208, 12-18.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| pyrazole | - |
Canis lupus familiaris |  |
| pyrazole | - |
Zea mays | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.019 | - |
formaldehyde | - |
Canis lupus familiaris | |
| 0.02 | - |
formaldehyde | - |
Zea mays | |
| 0.021 | - |
formaldehyde | - |
Zea mays | |
| 0.031 | - |
NAD+ | - |
Zea mays | |
| 0.031 | - |
NAD+ | - |
Canis lupus familiaris | |
| 0.037 | - |
glutathione | - |
Zea mays | |
| 0.062 | - |
glutathione | - |
Canis lupus familiaris | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 42000 | - |
2 * 42000, SDS-PAGE | Zea mays |
| 82000 | - |
gel filtration | Zea mays |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Zea mays | the enzyme may be involved in the detoxification of long-chain lipid peroxidation products | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Canis lupus familiaris | - |
- |
- |
| Zea mays | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Zea mays |
- |
Canis lupus familiaris |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| cell suspension culture | - |
Zea mays | - |
| lung | - |
Canis lupus familiaris | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 4.68 | - |
- |
Zea mays |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 10-hydroxydodecanoic acid + glutathione + NAD+ | - |
Zea mays | ? | - |
? | |
| 12-hydroxydodedecanoic acid + glutathione + NAD+ | - |
Zea mays | 12-oxododecanoic acid + ? | - |
? | |
| formaldehyde + glutathione + NAD+ | the true substrate is a hemimercaptal, S-hydroxymethylglutathione, spontaneously formed from formaldehyde and glutathione | Zea mays | S-formylglutathione + NADH + H+ | - |
? | |
| formaldehyde + glutathione + NAD+ | the true substrate is a hemimercaptal, S-hydroxymethylglutathione, spontaneously formed from formaldehyde and glutathione | Canis lupus familiaris | S-formylglutathione + NADH + H+ | - |
? | |
| additional information | the enzyme may be involved in the detoxification of long-chain lipid peroxidation products | Zea mays | ? | - |
? | |
| octanol + glutathione + NAD+ | octanol-1 | Zea mays | ? | - |
? | |
| pentanol + glutathione + NAD+ | - |
Zea mays | ? | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| dimer | 2 * 42000, SDS-PAGE | Zea mays |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 45 | - |
- |
Zea mays |
| 55 | - |
- |
Canis lupus familiaris |
Turnover Number [1/s]
| Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| additional information | - |
additional information | - |
Zea mays |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 8 | 9.5 | - |
Zea mays |
| 8 | 9.5 | - |
Canis lupus familiaris |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NAD+ | - |
Zea mays | |
| NAD+ | - |
Canis lupus familiaris | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
