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Literature summary for 1.1.1.284 extracted from

  • Yang, Z.N.; Bosron, W.F.; Hurley, T.D.
    Structure of human chi chi alcohol dehydrogenase: a glutathione-dependent formaldehyde dehydrogenase (1997), J. Mol. Biol., 265, 330-343.
    View publication on PubMed

Crystallization (Commentary)

Crystallization (Comment) Organism
crystal structure of the enzyme in a binary complex with NAD+(gamma) Homo sapiens

Metals/Ions

Metals/Ions Comment Organism Structure
Zinc contains a catalytic zinc ion Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
formaldehyde + glutathione + NAD+
-
Homo sapiens S-formylglutathione + NADH + H+
-
?

Cofactor

Cofactor Comment Organism Structure
NAD+ His47 may function both as a catalytic base for proton transfer and in the binding of the adenosine phosphate of NAD(H) Homo sapiens