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Literature summary for 1.1.1.28 extracted from

  • Wienstroer, J.; Engqvist, M.K.; Kunz, H.H.; Fluegge, U.I.; Maurino, V.G.
    D-Lactate dehydrogenase as a marker gene allows positive selection of transgenic plants (2012), FEBS Lett., 586, 36-40.
    View publication on PubMed

Application

Application Comment Organism
molecular biology D-lactate dehydrogenase is useful as a marker gene allowing positive selection of transgenic plants Arabidopsis thaliana

Protein Variants

Protein Variants Comment Organism
additional information at media D-lactate concentrations greater than 5-10 mM the development of wild-type plants is arrested shortly after germination whereas plants overexpressing the endogenous D-lactate dehydrogenase detoxify D-lactate to pyruvate and survive, phenotypes, overview Arabidopsis thaliana

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(R)-lactate + NAD+ Arabidopsis thaliana
-
pyruvate + NADH + H+
-
r
(R)-lactate + NAD+ Arabidopsis thaliana Columbia-0
-
pyruvate + NADH + H+
-
r

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana
-
-
-
Arabidopsis thaliana Columbia-0
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
leaf
-
Arabidopsis thaliana
-
seedling
-
Arabidopsis thaliana
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(R)-lactate + NAD+
-
Arabidopsis thaliana pyruvate + NADH + H+
-
r
(R)-lactate + NAD+
-
Arabidopsis thaliana Columbia-0 pyruvate + NADH + H+
-
r

Synonyms

Synonyms Comment Organism
D-LDH
-
Arabidopsis thaliana

Cofactor

Cofactor Comment Organism Structure
NAD+
-
Arabidopsis thaliana
NADH
-
Arabidopsis thaliana