KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0031 | - |
1-deoxy-D-xylulose 5-phosphate | - |
Escherichia coli | |
0.00423 | - |
4-[2H]-D-1-deoxyxylulose-5-phosphate | - |
Escherichia coli | |
0.00537 | - |
3-[2H]-D-1-deoxyxylulose-5-phosphate | - |
Escherichia coli |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
2-C-methyl-D-erythritol 4-phosphate + NADP+ = 1-deoxy-D-xylulose 5-phosphate + NADPH + H+ | retro-aldol/aldol mechanism | Escherichia coli |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
1-deoxy-D-xylulose 5-phosphate + NAD(P)H + H+ | inverse secondary kinetic isotope effects for both 3-[2H] and 4-[2H]-D-1-deoxyxylulose-5-phosphate during DXR-catalyzed isomerization indicates that the enzyme operates through a retro-aldol/aldol mechanism | Escherichia coli | 2-C-methyl-D-erythritol 4-phosphate + NAD(P)+ | - |
? | |
3-[2H]-D-1-deoxyxylulose-5-phosphate + NAD(P)H | - |
Escherichia coli | ? + NAD(P)+ | - |
? | |
4-[2H]-D-1-deoxyxylulose-5-phosphate + NAD(P)H | - |
Escherichia coli | ? + NAD(P)+ | - |
? |