Literature summary for 1.1.1.252 extracted from

Perpetua, N.S.; Kubo, Y.; Yasuda, N.; Takano, Y.; Furusawa, I.
Cloning and characterization of a melanin biosynthetic THR1 reductase gene essential for appressorial penetration of Colletotrichum lagenarium (1996), Mol. Plant Microbe Interact., 9, 323-329.

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Cloned(Commentary)

Cloned (Comment)	Organism
-	Colletotrichum lagenaria

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
1,3,6,8-Tetrahydroxynaphthalene + NADPH	Colletotrichum lagenaria	the enzyme is involved in melanin biosynthesis and pathogenicity	Scytalone + NADP+	-	?

Organism

Organism	UniProt	Comment	Textmining
Colletotrichum lagenaria	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1,3,6,8-Tetrahydroxynaphthalene + NADPH	the enzyme is involved in melanin biosynthesis and pathogenicity	Colletotrichum lagenaria	Scytalone + NADP+	-	?
1,3,8-trihydroxynaphthalene + NADPH + H+	-	Colletotrichum lagenaria	vermelone + NADP+	-	?

Cofactor

Cofactor	Comment	Organism	Structure
NADPH	-	Colletotrichum lagenaria

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Release 2023.1 (January 2023)