Literature summary for 1.1.1.248 extracted from

Ziegler, J.; Facchini, P.J.; Geissler, R.; Schmidt, J.; Ammer, C.; Kramell, R.; Voigtlaender, S.; Gesell, A.; Pienkny, S.; Brandt, W.
Evolution of morphine biosynthesis in opium poppy (2009), Phytochemistry, 70, 1696-1707.

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Cloned(Commentary)

Cloned (Comment)	Organism
heterologously overexpressed in its active form from Papaver somniferum	Papaver somniferum

Organism

Organism	UniProt	Comment	Textmining
Papaver arenarium	-	-	-
Papaver bracteatum	A4UHT7	-	-
Papaver pilosum	-	-	-
Papaver pyrenaicum	-	-	-
Papaver somniferum	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	occurrence of active SalR homologue in Papaver pilosum, although it does not produce salutaridine or any other promorphinan alkaloid	Papaver pilosum	?	-	?
additional information	occurrence of active SalR homologue in Papaver pyrenaicum, although it does not produce salutaridine or any other promorphinan alkaloid	Papaver pyrenaicum	?	-	?
salutaridine + NADPH + H+	high levels of SalR expression in all Papaver somniferum varieties	Papaver somniferum	(7S)-salutaridinol + NADP+	-	?
salutaridine + NADPH + H+	moderate levels of SalR expression in Papaver arenarium	Papaver arenarium	(7S)-salutaridinol + NADP+	-	?
salutaridine + NADPH + H+	moderate levels of SalR expression in Papaver bracteatum	Papaver bracteatum	(7S)-salutaridinol + NADP+	-	?

Synonyms

Synonyms	Comment	Organism
SalR	-	Papaver somniferum
SalR	-	Papaver bracteatum
SalR	-	Papaver arenarium
SalR	-	Papaver pilosum
SalR	-	Papaver pyrenaicum

Cofactor

Cofactor	Comment	Organism	Structure
NADPH	-	Papaver somniferum
NADPH	-	Papaver bracteatum
NADPH	-	Papaver arenarium
NADPH	-	Papaver pilosum
NADPH	-	Papaver pyrenaicum

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Release 2023.1 (January 2023)