Inhibitors | Comment | Organism | Structure |
---|---|---|---|
piperine | stronger inhibition with intestinal cell enzyme than with rat liver enzyme | Cavia porcellus | |
piperine | non-competitive, reversible, non-pH-dependent, 90% inhibition at concentration 0.05 mM and 10% inhibition at concentration 0.01 mM | Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.015 | - |
UDPglucose | pH 9.4 | Rattus norvegicus | |
0.035 | - |
UDPglucose | pH 8.6 | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Rattus norvegicus | - |
- |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
UDPglucose + NAD+ + H2O | Cavia porcellus | - |
UDPglucuronate + NADH | - |
? | |
UDPglucose + NAD+ + H2O | Rattus norvegicus | - |
UDPglucuronate + NADH | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Cavia porcellus | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
partial | Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Cavia porcellus | - |
liver | - |
Rattus norvegicus | - |
small intestine | - |
Cavia porcellus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
3-OH-benzopyrene + NAD+ | - |
Rattus norvegicus | ? | - |
? | |
UDP-glucose + 2 NAD+ + H2O | - |
Cavia porcellus | UDP-glucuronate + 2 NADH + 2 H+ | - |
? | |
UDP-glucose + 2 NAD+ + H2O | - |
Rattus norvegicus | UDP-glucuronate + 2 NADH + 2 H+ | - |
? | |
UDPglucose + NAD+ + H2O | - |
Cavia porcellus | UDPglucuronate + NADH | - |
? | |
UDPglucose + NAD+ + H2O | - |
Rattus norvegicus | UDPglucuronate + NADH | - |
? |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8.6 | - |
two pH optima, pH 8.6 and pH 9.4 | Rattus norvegicus |
9.4 | - |
two pH optima, pH 8.6 and pH 9.4 | Rattus norvegicus |