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Literature summary for 1.1.1.21 extracted from

  • Jiang, T.; Che, Q.; Lin, Y.; Li, H.; Zhang, N.
    Aldose reductase regulates TGF-beta1-induced production of fibronectin and type IV collagen in cultured rat mesangial cells (2006), Nephrology, 11, 105-112.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expression in rat renal mesangial cells Homo sapiens

Protein Variants

Protein Variants Comment Organism
additional information the recombinnat enzyme regulates TGF-beta1-induced production of fibronectin and type IV collagen in transformed cultured rat mesangial cells, detailed overview Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
aldose + NADPH + H+ Homo sapiens
-
alditol + NADP+
-
?
additional information Homo sapiens the enzyme regulates TGF-beta1-induced production of fibronectin and type IV collagen, overview ?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
aldose + NADPH + H+
-
Homo sapiens alditol + NADP+
-
?
additional information the enzyme regulates TGF-beta1-induced production of fibronectin and type IV collagen, overview Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
aldose reductase
-
Homo sapiens

Cofactor

Cofactor Comment Organism Structure
NADPH
-
Homo sapiens