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Literature summary for 1.1.1.206 extracted from

  • Dehghan, E.; Shahriari Ahmadi, F.; Ghotbi Ravandi, E.; Reed, D.W.; Covello, P.S.; Bahrami, A.R.
    An atypical pattern of accumulation of scopolamine and other tropane alkaloids and expression of alkaloid pathway genes in Hyoscyamus senecionis (2013), Plant Physiol. Biochem., 70C, 188-194.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
tropinone + NADPH + H+ Hyoscyamus muticus tropinone reductase II pseudotropine + NADP+
-
?
tropinone + NADPH + H+ Hyoscyamus senecionis tropinone reductase II pseudotropine + NADP+
-
?

Organism

Organism UniProt Comment Textmining
Hyoscyamus muticus
-
-
-
Hyoscyamus senecionis
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
leaf hyoscyamine is the main tropane alkaloid of the leaf and root of Hyoscyamus muticus Hyoscyamus muticus
-
leaf scopolamine is the main tropane alkaloid compound in Hyoscyamus senecionis leaves Hyoscyamus senecionis
-
root hyoscyamine is the main tropane alkaloid of the leaf and root of Hyoscyamus muticus Hyoscyamus muticus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
tropinone + NADPH + H+ tropinone reductase II Hyoscyamus muticus pseudotropine + NADP+
-
?
tropinone + NADPH + H+ tropinone reductase II Hyoscyamus senecionis pseudotropine + NADP+
-
?

Synonyms

Synonyms Comment Organism
tropinone reductase II
-
Hyoscyamus muticus
tropinone reductase II
-
Hyoscyamus senecionis

Cofactor

Cofactor Comment Organism Structure
NADPH
-
Hyoscyamus muticus
NADPH
-
Hyoscyamus senecionis

General Information

General Information Comment Organism
metabolism tropinone reductase II is part of biosynthesis of calystegines, overview. Hyoscyamine is the main tropane alkaloid of the leaf and root of Hyoscyamus muticus. Higher amounts of littorine as an intermediate compound in the pathway, and 3'-hydroxylittorine are accumulated in roots than in other organs Hyoscyamus muticus
metabolism tropinone reductase II is part of biosynthesis of calystegines, overview. Scopolamine is the main tropane alkaloid compound in Hyoscyamus senecionis leaves. Higher amounts of littorine as an intermediate compound in the pathway, and 3'-hydroxylittorine are accumulated in roots than in other organs Hyoscyamus senecionis