Inhibitors | Comment | Organism | Structure |
---|---|---|---|
6-Chloro-9-beta-D-ribofuranosylpurine 5 '-phosphate | acts at the IMP binding site | Sus scrofa | |
AMP | - |
Sus scrofa | |
GMP | - |
Sus scrofa | |
NAD+ | 44% inhibition at 1.5 M | Sus scrofa | |
NH4+ | 25% inhibition at 2.12 M | Sus scrofa | |
xanthosine 5'-phosphate | - |
Sus scrofa |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.007 | - |
IMP | - |
Sus scrofa | |
0.016 | - |
NAD+ | - |
Sus scrofa |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
K+ | - |
Sus scrofa |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
57000 | - |
SDS-PAGE | Sus scrofa |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Sus scrofa | - |
- |
- |
Purification (Comment) | Organism |
---|---|
homogeneity | Sus scrofa |
Source Tissue | Comment | Organism | Textmining |
---|
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.57 | - |
- |
Sus scrofa |
Storage Stability | Organism |
---|---|
-20, no significant loss of activity for serveral weeks after ammonium sulfate precipitation, no loss of activity after Sephacryl S400 chromatography | Sus scrofa |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
IMP + NAD+ + H2O | - |
Sus scrofa | XMP + NADH + H+ | - |
r |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8 | - |
- |
Sus scrofa |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
7.5 | 9 | pH 7.5: about 50% of activity maximum, pH 9: about 50% of activity maximum | Sus scrofa |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.05 | - |
GMP | - |
Sus scrofa | |
0.085 | - |
xanthosine 5'-phosphate | - |
Sus scrofa | |
0.282 | - |
AMP | - |
Sus scrofa |