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Literature summary for 1.1.1.205 extracted from

  • Brox, L.W.; Hampton, A.
    Inosine-5-phosphate dehydrogenase of Aerobacter aerogenes. Studies of tertiary structure (1970), Biochim. Biophys. Acta, 206, 215-223.
    View publication on PubMed

General Stability

General Stability Organism
50% loss of activity when freeze-dried Klebsiella aerogenes

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
90000 100000 basic catalytic molecular species, the species of this MW are of more than one type, under following conditions 2 species of indicated MW are present in approximately equal amount: 56000 and 95000 in 0.02 M phosphate at pH 7.4, 185000 and 300000 in 0.1 M Tris-citrate at pH 8.1, 185000 and 300000 in 0.02 M Tris-citrate at pH 7.4 or 8.1 containing 0.1 M KCl, 0.1 M NaCl or 0.25 M KCl, 90000 and 180000 in 0.38 M Tris-HCl, ultracentrifugation, sucrose density gradient sedimentation Klebsiella aerogenes

Organism

Organism UniProt Comment Textmining
Klebsiella aerogenes
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Klebsiella aerogenes

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
inosine 5'-phosphate + NAD+ + H2O
-
Klebsiella aerogenes xanthosine 5'-phosphate + NADH
-
?

Cofactor

Cofactor Comment Organism Structure
NAD+
-
Klebsiella aerogenes