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Literature summary for 1.1.1.202 extracted from

  • Seo, J.W.; Seo, M.Y.; Oh, B.R.; Heo, S.Y.; Baek, J.O.; Rairakhwada, D.; Luo, L.H.; Hong, W.K.; Kim, C.H.
    Identification and utilization of a 1,3-propanediol oxidoreductase isoenzyme for production of 1,3-propanediol from glycerol in Klebsiella pneumoniae (2009), Appl. Microbiol. Biotechnol., 85, 659-666.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
plasmid including Escherichia coli yqhD introduced into Klebsiella pneumoniae AK mutant strain defective in in 1,3-PD oxidoreductase activity (DhaT) Escherichia coli

Protein Variants

Protein Variants Comment Organism
additional information Klebsiella pneumoniae AK mutant strain defective in 1,3-PD oxidoreductase activity (DhaT). The Escherichia coli yqhD homolog can replace the function of DhaT. The yqhD homolog restores propane-1,3-diol production and 1,3-PD oxidoreductase activity in the mutant Klebsiella pneumoniae strain defective in DhaT. Level of propane-1,3-diol production during batch fermentation in the recombinant strain is comparable to that of the parent strain Klebsiella pneumoniae

Organism

Organism UniProt Comment Textmining
Escherichia coli
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Klebsiella pneumoniae
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3-hydroxypropanal + NADPH + H+ the Escherichia coli yqhD homolog can replace the function of DhaT in the Klebsiella pneumoniae AK mutant strain defective in 1,3-PD oxidoreductase activity (DhaT). The yqhD homolog restores propane-1,3-diol production and 1,3-PD oxidoreductase activity. Level of propane-1,3-diol production during batch fermentation in the recombinant strain is comparable to that of the parent strain Escherichia coli propane-1,3-diol + NADP+
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Synonyms

Synonyms Comment Organism
1,3-PD oxidoreductase
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Escherichia coli
1,3-PD oxidoreductase
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Klebsiella pneumoniae
1,3-propanediol oxidoreductase
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Escherichia coli
1,3-propanediol oxidoreductase
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Klebsiella pneumoniae
DhaT
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Klebsiella pneumoniae
YqhD
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Escherichia coli

Cofactor

Cofactor Comment Organism Structure
NADPH
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Escherichia coli