Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
3alpha,7beta,12alpha-trihydroxy-5beta-cholanoic acid + NADP+ | Collinsella aerofaciens | partially reversible, poor substrate | 3alpha,12alpha-dihydroxy-7-keto-5beta-cholanoic acid + NADPH | - |
r | |
3alpha,7beta,12alpha-trihydroxy-5beta-cholanoic acid + NADP+ | Collinsella aerofaciens | ursocholic acid | 3alpha,12alpha-dihydroxy-7-keto-5beta-cholanoic acid + NADPH | - |
r | |
3alpha,7beta-dihydroxy-5beta-cholanoic acid + NADP+ | Collinsella aerofaciens | ursodeoxycholic acid | 3alpha-hydroxy-7-oxo-5beta-cholanoic acid + NADPH | - |
r | |
3alpha,7beta-dihydroxy-5beta-cholanoic acid + NADP+ | Collinsella aerofaciens | partially reversible | 3alpha-hydroxy-7-oxo-5beta-cholanoic acid + NADPH | - |
r | |
3alpha,7beta-dihydroxy-5beta-cholanoyl taurine + NADP+ | Collinsella aerofaciens | partially reversible, poore substrate | 3alpha-hydroxy-7-keto-5beta-cholanoyl taurine + NADPH | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Collinsella aerofaciens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
cell culture | - |
Collinsella aerofaciens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
3alpha,7beta,12alpha-trihydroxy-5beta-cholanoic acid + NADP+ | partially reversible, poor substrate | Collinsella aerofaciens | 3alpha,12alpha-dihydroxy-7-keto-5beta-cholanoic acid + NADPH | - |
r | |
3alpha,7beta,12alpha-trihydroxy-5beta-cholanoic acid + NADP+ | ursocholic acid | Collinsella aerofaciens | 3alpha,12alpha-dihydroxy-7-keto-5beta-cholanoic acid + NADPH | - |
r | |
3alpha,7beta-dihydroxy-5beta-cholanoic acid + NADP+ | ursodeoxycholic acid | Collinsella aerofaciens | 3alpha-hydroxy-7-oxo-5beta-cholanoic acid + NADPH | - |
r | |
3alpha,7beta-dihydroxy-5beta-cholanoic acid + NADP+ | partially reversible | Collinsella aerofaciens | 3alpha-hydroxy-7-oxo-5beta-cholanoic acid + NADPH | - |
r | |
3alpha,7beta-dihydroxy-5beta-cholanoyl taurine + NADP+ | partially reversible, poore substrate | Collinsella aerofaciens | 3alpha-hydroxy-7-keto-5beta-cholanoyl taurine + NADPH | - |
r |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
9.8 | 10.3 | - |
Collinsella aerofaciens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADP+ | no activity with NAD+ | Collinsella aerofaciens |