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Literature summary for 1.1.1.2 extracted from

  • Hartz, T.K.; Houston, M.R.; Lockwood, L.B.
    Substrate specificity and kinetic properties of NADP+-dependent alcohol dehydrogenase of Phycomyces blakesleeanus (1978), Mycologia, 70, 586-593.
No PubMed abstract available

Inhibitors

Inhibitors Comment Organism Structure
p-mercuribenzoate
-
Candida tropicalis
p-mercuribenzoate
-
Cucumis melo
p-mercuribenzoate
-
Mycobacterium tuberculosis
p-mercuribenzoate
-
Neurospora crassa
p-mercuribenzoate
-
Penicillium urticae
p-mercuribenzoate
-
Phycomyces blakesleeanus
p-mercuribenzoate
-
Pseudomonas aeruginosa
p-mercuribenzoate
-
Rhizopus arrhizus
p-mercuribenzoate
-
Solanum tuberosum
pyrazole
-
Phycomyces blakesleeanus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.00246
-
1-Heptanol
-
Phycomyces blakesleeanus
0.00251
-
1-Hexanol
-
Phycomyces blakesleeanus
0.00273
-
1-Pentanol
-
Phycomyces blakesleeanus
0.0033
-
n-butanol
-
Phycomyces blakesleeanus
0.00522
-
1-propanol
-
Phycomyces blakesleeanus
0.013
-
ethanol NADP+ Phycomyces blakesleeanus
0.0198
-
ethanol
-
Phycomyces blakesleeanus

Organism

Organism UniProt Comment Textmining
Candida tropicalis
-
-
-
Cucumis melo
-
-
-
Mycobacterium tuberculosis
-
-
-
Neurospora crassa
-
-
-
Penicillium urticae
-
-
-
Phycomyces blakesleeanus
-
-
-
Pseudomonas aeruginosa
-
-
-
Rhizopus arrhizus
-
-
-
Saccharomyces cerevisiae
-
yeast
-
Solanum tuberosum
-
-
-

Purification (Commentary)

Purification (Comment) Organism
partially Phycomyces blakesleeanus

Source Tissue

Source Tissue Comment Organism Textmining
tuber
-
Solanum tuberosum
-

Storage Stability

Storage Stability Organism
0°C stable in the frozen state for 3-4 months without any appreciable loss in activity Phycomyces blakesleeanus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1-pentanol + NADP+
-
Phycomyces blakesleeanus n-pentanal + NADPH
-
r
2-propen-1-ol + NADP+
-
Phycomyces blakesleeanus acrylaldehyde + NADPH
-
r
ethanol + NADP+
-
Saccharomyces cerevisiae acetaldehyde + NADPH + H+
-
r
ethanol + NADP+
-
Phycomyces blakesleeanus acetaldehyde + NADPH + H+
-
r
formaldehyde + NADPH methanal Phycomyces blakesleeanus methanol + NADP+
-
?
n-butanol + NADP+
-
Phycomyces blakesleeanus butyraldehyde + NADPH
-
r
n-heptanol + NADP+
-
Saccharomyces cerevisiae n-heptanal + NADPH
-
r
n-heptanol + NADP+
-
Phycomyces blakesleeanus n-heptanal + NADPH
-
r
n-hexanol + NADP+
-
Saccharomyces cerevisiae n-hexanal + NADPH
-
r
n-hexanol + NADP+
-
Phycomyces blakesleeanus n-hexanal + NADPH
-
r
n-propanol + NADP+
-
Phycomyces blakesleeanus propionaldehyde + NADPH
-
r