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Literature summary for 1.1.1.2 extracted from

  • Shinoda, M.; Mori, S.; Shintani, S.; Ishikura, S.; Hara, A.
    Inhibition of human aldehyde reductase by drugs for testing the function of liver and kidney (1999), Biol. Pharm. Bull., 22, 741-744.
    View publication on PubMed

Application

Application Comment Organism
medicine
-
Sus scrofa
medicine drugs for testing function of liver and kidney Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
2,3-dimethylsuccinic acid
-
Homo sapiens
2,3-dimethylsuccinic acid
-
Sus scrofa
Amaranth
-
Homo sapiens
arachidonic acid
-
Homo sapiens
Diphenic acid
-
Homo sapiens
Ethacrynic acid
-
Homo sapiens
haematin
-
Homo sapiens
indigo carmine
-
Homo sapiens
Indocyanine green
-
Homo sapiens
phenolsulfophthalein
-
Homo sapiens
Rose bengal
-
Homo sapiens
sodium valproate
-
Homo sapiens
Sulfobromophthalein
-
Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
D-glucuronate + NADPH Homo sapiens
-
L-gulonate + NADP+
-
r
D-glucuronate + NADPH Sus scrofa
-
L-gulonate + NADP+
-
r

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
human
-
Sus scrofa
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
kidney
-
Homo sapiens
-
kidney
-
Sus scrofa
-
liver
-
Homo sapiens
-
liver
-
Sus scrofa
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3-deoxyglucosone + NADPH
-
Homo sapiens ? + NADP+
-
r
D-glucuronate + NADPH
-
Homo sapiens L-gulonate + NADP+
-
r
D-glucuronate + NADPH
-
Sus scrofa L-gulonate + NADP+
-
r
iodohexadecanal + NADPH
-
Homo sapiens iodohexadecanol + NADP+
-
r
methylglyoxal + NADPH
-
Homo sapiens ? + NADP+
-
r
methylglyoxal + NADPH
-
Sus scrofa ? + NADP+
-
r