Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | inhibitors such as alrestatin, ponalrestat, and EBPC exhibit distinct and characteristic inhibition of prostaglandin F2alpha production in different cell models | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P15121 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
cardiomyocyte | - |
Homo sapiens | - |
endothelium | - |
Homo sapiens | - |
prostate | - |
Homo sapiens | - |
uterine endometrium | - |
Homo sapiens | - |
vascular smooth muscle cell | - |
Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
AKR1B1 | - |
Homo sapiens |
ALDR1 | - |
Homo sapiens |
ALR2 | - |
Homo sapiens |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | interleukin IL-1beta is able to upregulate COX-2 and AKR1B1 proteins as well as prostaglandin F2alpha production under normal glucose concentrations. The promoter activity of AKR1B1 gene is increased by IL-1beta particularly around the multiple stress response region | up |