Inhibitors | Comment | Organism | Structure |
---|---|---|---|
9,10-phenanthroline | strong inhibition | Sus scrofa | |
additional information | adrenochrome is a poor inhibitor | Sus scrofa |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | kinetics | Sus scrofa | |
0.003 | - |
9,10-phenanthroline | pH 5.5, 37°C | Sus scrofa | |
0.083 | - |
Adrenochrome | pH 6.0, 37°C | Sus scrofa |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Sus scrofa | 5829 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-benzoylpyridine + NADPH + H+ | Sus scrofa | stereoselective reduction | S-(-)-phenylpyridin-4-yl-methynol + NADP+ | - |
? | |
all-trans retinal + NADPH + H+ | Sus scrofa | - |
all-trans retinol + NADP+ | - |
? | |
additional information | Sus scrofa | the enzyme plays a role in superoxide formation through redox cycling of 9,10-phenanthrenequinone and, to a lesser extent, of adrenochrome in pig heart | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Sus scrofa | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
heart | - |
Sus scrofa | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-benzoylpyridine + NADPH + H+ | stereoselective reduction | Sus scrofa | S-(-)-phenylpyridin-4-yl-methynol + NADP+ | - |
? | |
9,10-phenanthroline + NADPH + H+ | stereoselective reduction | Sus scrofa | ? | - |
? | |
adrenochrome + NADPH + H+ | stereoselective reduction | Sus scrofa | ? | - |
? | |
all-trans retinal + NADPH + H+ | - |
Sus scrofa | all-trans retinol + NADP+ | - |
? | |
additional information | the enzyme plays a role in superoxide formation through redox cycling of 9,10-phenanthrenequinone and, to a lesser extent, of adrenochrome in pig heart | Sus scrofa | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PHCR | - |
Sus scrofa |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Sus scrofa |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
5.5 | - |
with 9,10-phenanthroline as substrate | Sus scrofa |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | - |
Sus scrofa |