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Literature summary for 1.1.1.184 extracted from
- Purification and properties of prostaglandin 9-ketoreductase from pig and human kidney. Identity with human carbonyl reductase (1992), Eur. J. Biochem., 206, 491-502.
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.002 | - |
9,10-phenanthrenquinone | - |
Sus scrofa |  |
| 0.16 | - |
prostaglandin E2 | - |
Sus scrofa | |
| 0.31 | - |
menadione | - |
Sus scrofa | |
| 0.45 | - |
4-nitrobenzaldehyde | - |
Sus scrofa | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Zinc | - |
Homo sapiens | |
| Zinc | - |
Sus scrofa | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| additional information | - |
amino acid composition | Homo sapiens |
| additional information | - |
amino acid composition | Sus scrofa |
| 28000 | 32000 | gel filtration, SDS-PAGE | Sus scrofa |
| 34000 | - |
gel filtration, SDS-PAGE | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
| Sus scrofa | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Homo sapiens |
- |
Sus scrofa |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| kidney | - |
Homo sapiens | - |
| kidney | - |
Sus scrofa | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 4-nitrobenzaldehyde + NADPH | - |
Homo sapiens | 4-nitrobenzyl alcohol + NADP+ | - |
? | |
| 4-nitrobenzaldehyde + NADPH | - |
Sus scrofa | 4-nitrobenzyl alcohol + NADP+ | - |
? | |
| 9,10-phenanthrenequinone + NADPH | - |
Homo sapiens | ? | - |
? | |
| 9,10-phenanthrenequinone + NADPH | - |
Sus scrofa | ? | - |
? | |
| menadione + NADPH | - |
Homo sapiens | ? | - |
? | |
| menadione + NADPH | - |
Sus scrofa | ? | - |
? | |
| additional information | - |
Homo sapiens | ? | - |
? | |
| additional information | catalyzes pro-S stereoselective hydrogen transfer from NADPH | Sus scrofa | ? | - |
? | |
| NADPH + H+ + oxidized 2,6-dichlorophenolindophenol | - |
Homo sapiens | NADP+ + reduced 2,6-dichlorophenolindophenol | - |
? | |
| NADPH + H+ + oxidized 2,6-dichlorophenolindophenol | - |
Sus scrofa | NADP+ + reduced 2,6-dichlorophenolindophenol | - |
? | |
| phenylglyoxal + NADPH | - |
Homo sapiens | ? | - |
? | |
| phenylglyoxal + NADPH | - |
Sus scrofa | ? | - |
? | |
| prostaglandin E2 + NADPH + H+ | - |
Sus scrofa | prostaglandin F2alpha + NADP+ | - |
r | |
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