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Literature summary for 1.1.1.184 extracted from
- Purification and catalytic properties of a tetrameric carbonyl reductase from rabbit heart (1999), J. Biochem., 125, 41-47.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Cibacron blue | - |
Oryctolagus cuniculus |  |
| NADP+ | - |
Oryctolagus cuniculus | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.006 | - |
NADPH | - |
Oryctolagus cuniculus | |
| 0.18 | - |
menadione | - |
Oryctolagus cuniculus | |
| 0.33 | - |
3-benzoylpyridine | - |
Oryctolagus cuniculus | |
| 0.59 | - |
4-Nitroacetophenone | - |
Oryctolagus cuniculus | |
| 0.63 | - |
3-benzoylpyridine | - |
Oryctolagus cuniculus | |
| 0.9 | - |
Pyridine-4-aldehyde | - |
Oryctolagus cuniculus | |
| 1.55 | - |
4-acetylpyridine | - |
Oryctolagus cuniculus | |
| 1.7 | - |
2-benzoylpyridine | - |
Oryctolagus cuniculus | |
| 1.8 | - |
Pyridine-3-aldehyde | - |
Oryctolagus cuniculus | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 27000 | - |
4 * 27000, SDS-PAGE | Oryctolagus cuniculus |
| 110000 | - |
gel filtration | Oryctolagus cuniculus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Oryctolagus cuniculus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Oryctolagus cuniculus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| heart | - |
Oryctolagus cuniculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 2-benzoylpyridine + NADPH | - |
Oryctolagus cuniculus | ? | - |
? | |
| 3-benzoylpyridine + NADPH | - |
Oryctolagus cuniculus | ? | - |
? | |
| 4-acetylpyridine + NADPH | - |
Oryctolagus cuniculus | ? | - |
? | |
| 4-benzoylpyridine + NADPH | - |
Oryctolagus cuniculus | ? | - |
ir | |
| 4-nitroacetophenone + NADPH | - |
Oryctolagus cuniculus | ? | - |
? | |
| menadione + NADPH | - |
Oryctolagus cuniculus | ? | - |
? | |
| additional information | no activity with NADH | Oryctolagus cuniculus | ? | - |
? | |
| pyridine-3-aldehyde + NADPH | - |
Oryctolagus cuniculus | ? | - |
? | |
| pyridine-4-aldehyde + NADPH | - |
Oryctolagus cuniculus | ? | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| tetramer | 4 * 27000, SDS-PAGE | Oryctolagus cuniculus |
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Release 2023.1 (January 2023)
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