Inhibitors | Comment | Organism | Structure |
---|---|---|---|
chlorpromazine | - |
Rattus norvegicus | |
CuSO4 | - |
Rattus norvegicus | |
dicoumarol | - |
Rattus norvegicus | |
Disulfiram | - |
Rattus norvegicus | |
Ethacrynic acid | inhibition of enzyme forms V1, V2 and T3 | Rattus norvegicus | |
Furosemide | inhibition of V1, V2 and T3 | Rattus norvegicus | |
indomethacin | - |
Rattus norvegicus | |
p-hydroxymercuribenzoate | - |
Rattus norvegicus | |
quercetin | - |
Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | overview | Rattus norvegicus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
32000 | - |
x * 32000, enzyme form T1, SDS-PAGE | Rattus norvegicus |
33000 | - |
rat, different enzyme forms from testis and vas deferens, SDS-PAGE | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
2 forms from vas deferens: V1, V2 | Rattus norvegicus |
3 forms from testis: T1, T2, T3 | Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
testis | - |
Rattus norvegicus | - |
vas deferens | mucosal epithelium cells | Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-benzoylpyridine + NADPH | - |
Rattus norvegicus | ? | - |
? | |
additional information | overview | Rattus norvegicus | ? | - |
? | |
additional information | no activity with NADH | Rattus norvegicus | ? | - |
? | |
additional information | specificity of various enzyme forms | Rattus norvegicus | ? | - |
? | |
prostaglandin A1-GSH + NADPH | only enzyme forms T3, V1, V2 | Rattus norvegicus | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 32000, enzyme form T1, SDS-PAGE | Rattus norvegicus |
? | x * 33000, enzyme forms T2, T3, V1, V2, SDS-PAGE | Rattus norvegicus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADH | no activity with NADH | Rattus norvegicus | |
NADPH | - |
Rattus norvegicus |