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Literature summary for 1.1.1.17 extracted from

  • Fischer, R.; von Strandmann, R.P.; Hengstenberg, W.
    Mannitol-specific phosphoenolpyruvate-dependent phosphotransferase system of Enterococcus faecalis: Molecular cloning and nucleotide sequences of the enzyme III Mtl gene and the mannitol-1-phosphate dehydrogenase gene, expression in Escherichia coli, and comparison of the gene products with similar enzymes (1991), J. Bacteriol., 173, 3709-3715.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Enterococcus faecalis

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
40000
-
x * 40000, SDS-PAGE Enterococcus faecalis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
D-mannitol 1-phosphate + NAD+ Staphylococcus carnosus
-
D-fructose 6-phosphate + NADH + H+
-
?
D-mannitol 1-phosphate + NAD+ Enterococcus faecalis part of the phosphoenolpyruvate phosphotransferase system D-fructose 6-phosphate + NADH + H+
-
?

Organism

Organism UniProt Comment Textmining
Enterococcus faecalis
-
-
-
Staphylococcus carnosus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
cell culture
-
Enterococcus faecalis
-
cell culture
-
Staphylococcus carnosus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
D-mannitol 1-phosphate + NAD+
-
Staphylococcus carnosus D-fructose 6-phosphate + NADH + H+
-
?
D-mannitol 1-phosphate + NAD+ part of the phosphoenolpyruvate phosphotransferase system Enterococcus faecalis D-fructose 6-phosphate + NADH + H+
-
?

Subunits

Subunits Comment Organism
? x * 40000, SDS-PAGE Enterococcus faecalis

Cofactor

Cofactor Comment Organism Structure
NAD+
-
Enterococcus faecalis
NAD+
-
Staphylococcus carnosus