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Literature summary for 1.1.1.17 extracted from

  • Mehta, R.J.; Fare, L.R.; Shearer, M.E.; Nash, C.H.
    Mannitol oxidation in two Micromonospora isolates and in representative species of other actinomycetes (1977), Appl. Environ. Microbiol., 33, 1013-1015.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.1.1.17

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
D-mannitol 1-phosphate + NAD+ Amycolatopsis lactamdurans
-
 D-fructose 6-phosphate + NADH + H+
-
 ?
D-mannitol 1-phosphate + NAD+ Micromonospora sp.
-
 D-fructose 6-phosphate + NADH + H+
-
 ?

Organism

Organism UniProt Comment Textmining
Amycolatopsis lactamdurans
-
-
-
Micromonospora sp.
-
 strains BC-1751, BC-2079
-
no activity in Actinoplanes missouriensis
-
-
-
no activity in Mycobacterium smegmatis
-
-
-
no activity in Nocardia erythropolis
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
cell culture
-
 Amycolatopsis lactamdurans
-
cell culture
-
 Micromonospora sp.
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.03
-
 crude extract, D-mannitol 1-phosphate oxidation Amycolatopsis lactamdurans
0.03 0.05 crude extract, D-mannitol 1-phosphate oxidation Micromonospora sp.

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
D-mannitol 1-phosphate + dichlorophenolindophenol higher activity than for NAD+ Micromonospora sp. D-fructose 6-phosphate + reduced dichlorophenolindophenol
-
 ?
D-mannitol 1-phosphate + NAD+
-
 Amycolatopsis lactamdurans D-fructose 6-phosphate + NADH + H+
-
 ?
D-mannitol 1-phosphate + NAD+
-
 Micromonospora sp. D-fructose 6-phosphate + NADH + H+
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
9
-
-
 Micromonospora sp.
9.5
-
 dichlorophenolindophenol-linked assay Micromonospora sp.

Cofactor

Cofactor Comment Organism Structure
NAD+
-
 Amycolatopsis lactamdurans
NAD+
-
 Micromonospora sp.