Literature summary for 1.1.1.153 extracted from

Hirakawa, H.; Sawada, H.; Yamahama, Y.; Takikawa, S.; Shintaku, H.; Hara, A.; Mase, K.; Kondo, T.; Iino, T.
Expression analysis of the aldo-keto reductases involved in the novel biosynthetic pathway of tetrahydrobiopterin in human and mouse tissues (2009), J. Biochem., 146, 51-60.

Search for more literature for 1.1.1.153

Inhibitors

Inhibitors	Comment	Organism	Structure
N-acetylserotonin	activity is completely inhibited by the addition of 0.5 mM N-acetylserotonin	Homo sapiens
N-acetylserotonin	activity is completely inhibited by the addition of 0.5 mM N-acetylserotonin	Mus musculus

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-
Mus musculus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
liver	-	Mus musculus	-
liver	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
6-pyruvoyl tetrahydropterin + NADPH + H+	-	Mus musculus	1'-oxo-2'-L-hydroxypropyl-tetrahydropterin + NADP+	-	?
6-pyruvoyl tetrahydropterin + NADPH + H+	-	Homo sapiens	1'-oxo-2'-L-hydroxypropyl-tetrahydropterin + NADP+	-	?
sepiapterin + NADPH + H+	-	Mus musculus	7,8-dihydrobiopterin + NADP+	-	?
sepiapterin + NADPH + H+	-	Homo sapiens	7,8-dihydrobiopterin + NADP+	-	?

Synonyms

Synonyms	Comment	Organism
AKR1B1	-	Mus musculus
SPR	-	Mus musculus
SPR	-	Homo sapiens

Cofactor

Cofactor	Comment	Organism	Structure
NADPH	-	Mus musculus
NADPH	-	Homo sapiens

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)