Any feedback?
Literature summary for 1.1.1.153 extracted from
- Effect of antisense oligodeoxynucleotide for sepiapterin reductase on the viability of PC12 cells in the presence of exogenous carbonyl compounds (2003), Chem. Biol. Interact., 143-144, 583-586.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| host cells transfected with sense, antisense and inverse antisense oligodeoxynucleotides | Rattus norvegicus |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| N-acetylserotonin | - |
Rattus norvegicus |  |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 6-pyruvoyl tetrahydropterin + 2 NADPH + 2 H+ | Rattus norvegicus | final step in the synthesis of tetrahydrobiopterin, role in detoxification of exogenous carbonyl compounds suggested | tetrahydrobiopterin + NADP+ | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| PC-12 cell | cell culture model for catecholaminergic neurons | Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 1-phenyl-1,2-propanedione + NADPH | - |
Rattus norvegicus | ? | - |
? | |
| 6-pyruvoyl tetrahydropterin + 2 NADPH + 2 H+ | final step in the synthesis of tetrahydrobiopterin, role in detoxification of exogenous carbonyl compounds suggested | Rattus norvegicus | tetrahydrobiopterin + NADP+ | - |
? | |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NADPH | - |
Rattus norvegicus | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
