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Literature summary for 1.1.1.149 extracted from
- Aberrant pre-receptor regulation of estrogen and progesterone action in endometrial cancer (2009), Mol. Cell. Endocrinol., 301, 74-82.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| additional information | 20alpha-HSD is up-regulated in endometrial cancer | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| endometrial cancer cell line | - |
Homo sapiens | - |
| uterine endometrium | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| progesterone + NAD(P)H + H+ | - |
Homo sapiens | 20alpha-hydroxyprogesterone + NAD(P)+ | - |
ir |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| 20alpha-HSD | - |
Homo sapiens |
| AKR1C1 | - |
Homo sapiens |
| AKR1C3 | - |
Homo sapiens |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NAD(P)+ | - |
Homo sapiens | |
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Release 2023.1 (January 2023)
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