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Literature summary for 1.1.1.146 extracted from

  • Fernandino, J.I.; Hattori, R.S.; Kishii, A.; Struessmann, C.A.; Somoza, G.M.
    The cortisol and androgen pathways cross talk in high temperature-induced masculinization: the 11beta-hydroxysteroid dehydrogenase as a key enzyme (2012), Endocrinology, 153, 6003-6011.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Odontesthes bonariensis
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Synonyms

Synonyms Comment Organism
Hsd11B2
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Odontesthes bonariensis

Expression

Organism Comment Expression
Odontesthes bonariensis larvae reared at male-producing temperature, and cortisol treatment produce significant increases in isoform Hsd11B2 mRNA expression. Also, gonadal explants incubated in the presence of cortisol show increases of 11-ketotestosterone levels in the medium up