Inhibitors | Comment | Organism | Structure |
---|---|---|---|
bezafibrate | 23% inhibition at 0.01 mM, cell-based assay, pH not specified in the publication, temperature not specified in the publication | Mus musculus | |
Clofibrate | 18% inhibition at 0.01 mM, cell-based assay, pH not specified in the publication, temperature not specified in the publication | Mus musculus | |
fenofibrate | 82% inhibition at 0.01 mM, cell-based assay, pH not specified in the publication, temperature not specified in the publication | Mus musculus | |
fenofibric acid | 25% inhibition at 0.01 mM, cell-based assay, pH not specified in the publication, temperature not specified in the publication | Mus musculus | |
fenofibric acid cyclohexyl ester | 54% inhibition at 0.01 mM, cell-based assay, pH not specified in the publication, temperature not specified in the publication | Mus musculus | |
fenofibric acid ethylester | 85% inhibition at 0.01 mM, cell-based assay, pH not specified in the publication, temperature not specified in the publication | Mus musculus | |
fenofibric acid isobutylester | 75% inhibition at 0.01 mM, cell-based assay, pH not specified in the publication, temperature not specified in the publication | Mus musculus | |
fenofibric acid isopropyl amide | 54% inhibition at 0.01 mM, cell-based assay, pH not specified in the publication, temperature not specified in the publication | Mus musculus | |
fenofibric acid n-butylester | 64% inhibition at 0.01 mM, cell-based assay, pH not specified in the publication, temperature not specified in the publication | Mus musculus | |
gemfibrozil | 19% inhibition at 0.01 mM, cell-based assay, pH not specified in the publication, temperature not specified in the publication | Mus musculus | |
WY-14643 | 22% inhibition at 0.01 mM, cell-based assay, pH not specified in the publication, temperature not specified in the publication | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
C2C12 cell | differentiated into myotubes | Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
cortisone + NADPH + H+ | - |
Mus musculus | cortisol + NADP+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
11beta-hydroxysteroid dehydrogenase 1 | - |
Mus musculus |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0016 | - |
fenofibrate | 82% inhibition at 0.01 mM, cell-based assay, pH not specified in the publication, temperature not specified in the publication | Mus musculus | |
0.0031 | - |
fenofibric acid isobutylester | 75% inhibition at 0.01 mM, cell-based assay, pH not specified in the publication, temperature not specified in the publication | Mus musculus | |
0.0034 | - |
fenofibric acid ethylester | 85% inhibition at 0.01 mM, cell-based assay, pH not specified in the publication, temperature not specified in the publication | Mus musculus | |
0.0041 | - |
fenofibric acid n-butylester | 64% inhibition at 0.01 mM, cell-based assay, pH not specified in the publication, temperature not specified in the publication | Mus musculus | |
0.009 | - |
fenofibric acid isopropyl amide | 54% inhibition at 0.01 mM, cell-based assay, pH not specified in the publication, temperature not specified in the publication | Mus musculus | |
0.0091 | - |
fenofibric acid cyclohexyl ester | 54% inhibition at 0.01 mM, cell-based assay, pH not specified in the publication, temperature not specified in the publication | Mus musculus |